Neural interfacing
Flexible bioelectronics to restore organ function after spinal cord injury
Organ dysfunction is one of the most disabling consequences of spinal cord injury. We use conformable nerve cuff implants to record and stimulate nerve activity linked to organ state. Our aim is to understand how injury disrupts communication between the nervous system and organs such as the bladder, and to find ways of restoring that control with targeted neuromodulation. Building on this, we are developing closed-loop systems that detect changes in organ state and respond automatically, with the goal of creating therapies that return function to patients.
Tissue engineering
Biohybrid regenerative bioelectronics for nerve injury
Conventional neural interfaces struggle to form stable, selective connections with injured or regenerating nerves. We are developing biohybrid devices that combine compartmentalised flexible electronics with collagen-embedded cellular constructs that guide motor and sensory axons. As regenerating fibres grow into separate electrode compartments, the device can form a high-resolution interface that is selective for specific cell types. This approach could enable more natural control and sensory feedback after amputation or peripheral nerve injury.